I have not tested it fully with my iPad Pro M1 yet but my MIDI keyboard works with the USB ports at the same time as having my headphones connected to the headphone jack. HDMI with HDR works as well on my 4K TV with 60 Hz, but if you use Dolby Vision it will be reduced to 30 Hz (iPadOS limitation?). One problem I'm struggling with a bit is the pass-through charging. The original iPad charger (20W ?) with original cable does not work. The old iPad charger (12W) seems to work. I have another more powerful charger from AUKEY which seems to work also. So yes it can work but I have not figured it out completely yet, and I'm also new to USB-C.